NOD1 antibody [C2C3], C-term
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||108 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||nucleotide-binding oligomerization domain containing 1|
|Product Description||Rabbit polyclonal antibody to NOD1 (nucleotide-binding oligomerization domain containing 1)|
|Background||This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq]|
|Synonyms||CARD4 antibody, CLR7.1 antibody, NLRC1 antibody, NOD1 antibody, "NLR family, CARD domain containing 1 antibody", "caspase recruitment domain family, member 4 antibody", caspase recruitment domain-containing protein 4 antibody, nucleotide-binding oligomerization domain-containing protein 1 antibody, "nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1 antibody", nucleotide-binding oligomerization domain containing 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human NOD1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Bovine|
|Predict Reactivity Note||Mouse (81%), Rat (82%), Pig (87%), Bovine (87%)|