|Full Name||neuronal pentraxin II|
|Product Description||Rabbit Polyclonal antibody to NP2 (neuronal pentraxin II)|
|Background||This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq]|
|Synonyms||NARP antibody, NP-II antibody, NP2 antibody, NPTX2 antibody, neuronal activity-regulated pentaxin antibody, apexin antibody, neuronal pentraxin-2 antibody, neuronal pentraxin II antibody|
|Cellular Localization||Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NP2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Guinea pig|
|Predict Reactivity Note||Mouse (98%), Rat (98%), Guinea pig (95%)|