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NPR-C antibody [N3C3]

Anti-NPR-C antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX110023
Anti-NPR-C antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX110023
Anti-NPR-C antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX110023
Anti-NPR-C antibody [N3C3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX110023

Cat. No. GTX110023

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat, Rabbit, Chicken
Package
100 μl ($399),
25 μl ($169)
See all NPR-C products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

Predict Reactivity

Bovine(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.81 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human NPR-C. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1951016

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

natriuretic peptide receptor 3 , ANP-C , ANPR-C , ANPRC , C5orf23 , GUCY2B , NPR-C , NPRC

Cellular Localization

Membrane

Background

The family of natriuretic peptides (see MIM 108780) elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.[supplied by OMIM]

Database

Research Area

DATA IMAGES

Anti-NPR-C antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX110023

GTX110023 IHC-P Image

NPR-C antibody [N3C3] detects NPR-C protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded rat duodenum.
NPR-C stained by NPR-C antibody [N3C3] (GTX110023) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-NPR-C antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX110023

GTX110023 IHC-P Image

NPR-C antibody [N3C3] detects NPR-C protein at cell membrane and cytoplasm in mouse testis by immunohistochemical analysis.
Sample: Paraffin-embedded mouse testis.
NPR-C antibody [N3C3] (GTX110023) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-NPR-C antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX110023

GTX110023 IHC-P Image

NPR-C antibody [N3C3] detects NPR-C protein at cell membrane and cytoplasm in mouse duodenum by immunohistochemical analysis.
Sample: Paraffin-embedded mouse duodenum.
NPR-C antibody [N3C3] (GTX110023) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-NPR-C antibody [N3C3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX110023

GTX110023 ICC/IF Image

NPR-C antibody [N3C3] detects NPR-C protein at cytoplasm by immunofluorescent analysis.
Sample: A431 cells were fixed in ice-cold MeOH for 5 min.
Green: NPR-C protein stained by NPR-C antibody [N3C3] (GTX110023) diluted at 1:500.
Blue: Hoechst 33342 staining.

REFERENCE

Application Reference

Lopez-Morales MA et al. Mol Cell Endocrinol 2018; 472 : 43109 Molecular mechanisms underlying the neuroprotective role of atrial natriuretic peptide in experimental acute ischemic stroke.
Application : WB
Reactivity : Rat
Lopez-Morales MA et al. Eur J Pharmacol 2017; (Epub) Mechanisms involved in the increased sensitivity of the rabbit basilar artery to atrial natriuretic peptide in diabetes.
Application : WB
Reactivity : Rabbit
Kosla J et al. Gene 2013; 513 (1) : 90-100 Molecular analysis of the TGF-beta controlled gene expression program in chicken embryo dermal myofibroblasts.
Application : WB
Reactivity : Chicken
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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169