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1 .GTX89302 NMDAR1 antibody, Internal

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NMDAR1 antibody, Internal


  • Host / ClonalityGoat Polyclonal
  • ApplicationsWB
  • Species reactivityRat
Cat No: GTX89302
Package Price Qty
100 μgUSD 319.00
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  • Anti-NMDAR1 antibody, Internal used in Western blot. GTX89302
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  • Datasheet

  • Application Information: NMDAR1 antibody, Internal

Catalog Number GTX89302
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Product Name NMDAR1 antibody, Internal
See all NMDAR1 products
ApplicationsWB
Application NoteApprox 110kDa band observed in Rat Brain lysates (calculated MW of 105kDa according to NP_015566.1). Recommended concentration: 2-4µg/ml. A minor band of unknown identity was also consistently observed at 23-24kDa. This band was strong in Mouse Brain lysates and faint in Human Brain lysates. The band was successfully blocked by incubation with the immunising peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported? This antibody is expected to recognise all three reported isoforms (NP_000823.4; NP_067544.1; NP_015566.1).
Positive ControlsThe peptide used to product this antibody is available for purchase (Catalog Number:GTX89302-PEP).
Form SuppliedLiquid
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

  • Specifications: NMDAR1 antibody, Internal

Full Nameglutamate receptor, ionotropic, N-methyl D-aspartate 1
Product DescriptionGoat polyclonal antibody to NMDA receptor 1 / GRIN1
BackgroundNMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.
SynonymsNMDAR1, NMDA receptor1 / GRIN1, GRIN1, glutamate receptor, ionotropic, N-methyl D-aspartate 1, NMDA receptor 1, NR1, N-methyl-D-aspartate receptor channel, subunit zeta-1, NMDA receptor1, glutamate receptor, ionotropic, Nmethyl Daspartate1, NmethylDaspartate receptor channel, subunit zeta1, glutamate receptor, ionotropic, Nmethyl Daspartate 1, NMDA1, NMDA receptor 1 / GRIN1, glutamate [N
Cellular LocalizationEnriched in post-synaptic plasma membrane and post-synaptic densities.
SpecificityThis antibody is specific for NMDA receptor 1 / GRIN1.
HostGoat
ClonalityPolyclonal
IsotypeIgG
ImmunogenC-TQERVNNSNKKE
Antigen SpeciesHuman
Species ReactivityRat
Predicted Cross Reactivity species Predicted cross-reactivity:
    Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
    Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
 		Human, Mouse, Dog

  • Storage Conditions: NMDAR1 antibody, Internal

Storage BufferTris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction Aliquot and store at -20°C. Minimize freezing and thawing.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
NMDAR1 antibody, Internal validated data
  • Anti-NMDAR1 antibody, Internal used in Western blot. GTX89302
    • GTX89302 WB Image
      GTX89302 (2µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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  • Anti-NMDAR1 antibody, Internal used in Western blot. GTX89302
    • GTX89302 WB Image
      GTX89302 (2µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
      Top
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