NR2B antibody [C2C3], C-term
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||166 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain , rat brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||glutamate receptor, ionotropic, N-methyl D-aspartate 2B|
|Product Description||Rabbit Polyclonal antibody to NMDAR2B (glutamate receptor, ionotropic, N-methyl D-aspartate 2B)|
|Background||N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq]|
|Synonyms||MGC142178 antibody, MGC142180 antibody, NMDAR2B antibody, NR2B antibody, hNR3 antibody, GRIN2B antibody, glutamate receptor subunit epsilon-2 antibody, N-methyl-D-aspartate receptor subunit 3 antibody, glutamate [NMDA] receptor subunit epsilon-2 antibody, NR3 antibody, N-methyl D-aspartate receptor subtype 2B antibody, "glutamate receptor, ionotropic, N-methyl D-aspartate 2B antibody"|
|Cellular Localization||Cell membrane; Multi-pass membrane protein , Cell junction , synapse , postsynaptic cell membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human NMDAR2B. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Dog (97%), Bovine (91%)|