|Full Name||nuclear receptor subfamily 4, group A, member 3|
|Product Description||Rabbit Polyclonal antibody to NR4A3 (nuclear receptor subfamily 4, group A, member 3)|
|Background||This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Four transcript variants encoding three distinct isoforms have been identified for this gene. [provided by RefSeq]|
|Synonyms||CHN antibody, CSMF antibody, MINOR antibody, NOR1 antibody, TEC antibody, NR4A3 antibody, nuclear hormone receptor NOR-1 antibody, translocated in extraskeletal chondrosarcoma antibody, neuron-derived orphan receptor 1 antibody, nuclear receptor subfamily 4 group A member 3 antibody, "chondrosarcoma, extraskeletal myxoid, fused to EWS antibody", mitogen-induced nuclear orphan receptor antibody, "nuclear receptor subfamily 4, group A, member 3 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human NR4A3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (80%), Pig (82%)|