Full Name | nuclear receptor binding protein 1 |
Background | May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication. |
Synonyms | NRBP, NRBP1, MUDPNP, BCON3, MADM |
Cellular Localization | Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia. |
Specificity | GTX84000 is specific for human NRBP1. |
Host | Mouse |
Clonality | Monoclonal |
Clone Name | 7E2 |
Isotype | IgG2b |
Immunogen | Protein expressed in 293T cell transfected with human NRBP1 expression vector |
Antigen Species | Human |
Species Reactivity | Human, Dog, Monkey, Rat |
Conjugation | Unconjugated |