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NRF2 antibody

Orthogonal
Anti-NRF2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55732
Anti-NRF2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55732
Anti-NRF2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55732
Anti-NRF2 antibody used in Western Blot (WB). GTX55732
Anti-NRF2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55732
Anti-NRF2 antibody used in Western Blot (WB). GTX55732
Anti-NRF2 antibody used in Western Blot (WB). GTX55732
Anti-NRF2 antibody used in Western Blot (WB). GTX55732

Cat. No. GTX55732

Reference 4

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Ixodes scapularis, Human, Mouse, Rat
Package
100 μl ($399)
See all NRF2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

68 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 366-605 of human NFE2L2 (NP_006155.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887935

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

nuclear factor, erythroid 2 like 2 , HEBP1 , IMDDHH , NRF2

Cellular Localization

Cytoplasm, cytosol,Nucleus

Background

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-NRF2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55732

GTX55732 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX55732 NRF2 antibody.
Antigen retrieval : 10 mM citrate buffer (pH 6.0)
Dilution : 1:200

Anti-NRF2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55732

GTX55732 IHC-P Image

IHC-P analysis of human placenta tissue using GTX55732 NRF2 antibody.
Antigen retrieval : 10 mM citrate buffer (pH 6.0)
Dilution : 1:200

Anti-NRF2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55732

GTX55732 IHC-P Image

IHC-P analysis of human esophageal cancer tissue using GTX55732 NRF2 antibody.
Antigen retrieval : 10 mM citrate buffer (pH 6.0)
Dilution : 1:200

Anti-NRF2 antibody used in Western Blot (WB). GTX55732

GTX55732 WB Image

Orthogonal

WB analysis of treated and untreated cell lysates using GTX55732 NRF2 antibody.
Loading : 45 μg
Dilution : 1:1000

Anti-NRF2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55732

GTX55732 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX55732 NRF2 antibody.
Antigen retrieval : 10 mM citrate buffer (pH 6.0)
Dilution : 1:200

Anti-NRF2 antibody used in Western Blot (WB). GTX55732

GTX55732 WB Image

Orthogonal

The data was published in the journal Virulence in 2018. PMID: 29338543

Anti-NRF2 antibody used in Western Blot (WB). GTX55732

GTX55732 WB Image

The data was published in the 2021 in Nat Commun. PMID: 34140472

Anti-NRF2 antibody used in Western Blot (WB). GTX55732

GTX55732 WB Image

The data was published in the journal Virulence in 2018. PMID: 29338543

REFERENCE

Application Reference

Abd-Eldayem AM et al. Sci Rep 2024; 14 (1) : 7434 Cyclosporine-induced kidney damage was halted by sitagliptin and hesperidin via increasing Nrf2 and suppressing TNF-α, NF-κB, and Bax.
Chuang CY et al. Int J Mol Sci 2022; 23 (13) Deoxyshikonin Mediates Heme Oxygenase-1 Induction and Apoptotic Response via p38 Signaling in Tongue Cancer Cell Lines.
Application : WB
Reactivity : Human
Oliva Ch?vez AS et al. Nat Commun 2021; 12 (1) : 3696 Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection.
Application : WB
Chen WC et al. Virulence 2018; 9 (1) : 588-603 Lucidone suppresses dengue viral replication through the induction of heme oxygenase-1.
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399