NRF2 antibody [N2C2], Internal
|Applications||ICC/IF, IHC-P, IP, WB, ChIP assay|
Not tested in other applications.
| ChIP assay||Assay-dependent dilution
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||68 kDa (note)
|Observed Size||110 kDa.
The observed M.W. is based on the following publication. PMID:22703241
|Positive Controls||MDA-MB-231 NE , MDA-MB-231 NE treated tBHQ , 3xFlag-human NFE2L2-transfected 293T , C8D30|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||nuclear factor (erythroid-derived 2)-like 2|
|Product Description||Rabbit Polyclonal antibody to NRF2 (nuclear factor (erythroid-derived 2)-like 2)|
|Background||NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995 [PubMed 7868116]).[supplied by OMIM]|
|Synonyms||NRF2 antibody, NFE2L2 antibody, nuclear factor erythroid-derived 2-like 2 antibody, nuclear factor, erythroid derived 2, like 2 antibody, NF-E2-related factor 2 antibody, HEBP1 antibody, nuclear factor erythroid 2-related factor 2 antibody, NFE2-related factor 2 antibody, nuclear factor (erythroid-derived 2)-like 2 antibody|
|Cellular Localization||Cytoplasm , cytosol , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NRF2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rhesus Monkey (99%), Bovine (84%)|