|Full Name||sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)|
|Product Description||Rabbit Polyclonal antibody to NSMase2 (sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II))|
|Background||Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.|
|Synonyms||FLJ22593 antibody, MGC138443 antibody, NSMASE2 antibody, SMPD3 antibody, neutral sphingomyelinase 2 antibody, sphingomyelin phosphodiesterase 3 antibody, nSMase-2 antibody, neutral sphingomyelinase II antibody, "sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) antibody"|
|Cellular Localization||Golgi apparatus membrane; Multi-pass membrane protein , Cell membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NSMase2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (88%), Rat (89%), Bovine (87%)|