NT5C2 antibody [N2C1], Internal
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||65 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , mouse liver|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||5'-nucleotidase, cytosolic II|
|Product Description||Rabbit Polyclonal antibody to NT5C2 (5'-nucleotidase, cytosolic II)|
|Background||Purine 5-prime-nucleotidase (EC 220.127.116.11) preferentially hydrolyzes inosine 5-prime-monophosphate (IMP) and other purine nucleotides, and is allosterically activated by various compounds, including ATP. The enzyme is exclusively located in the cytoplasmic matrix of cells and may have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases.[supplied by OMIM]|
|Synonyms||GMP antibody, NT5B antibody, PNT5 antibody, cN-II antibody, NT5C2 antibody, cytosolic 5'-nucleotidase II antibody, "5'-nucleotidase (purine), cytosolic type B antibody", IMP-specific 5'-NT antibody, purine 5' nucleotidase antibody, cytosolic purine 5'-nucleotidase antibody, "5'-nucleotidase, cytosolic II antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NT5C2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Chicken (96%), Rhesus Monkey (100%), Bovine (100%)|