|Full Name||patatin-like phospholipase domain containing 6|
|Product Description||Rabbit Polyclonal antibody to NTE (patatin-like phospholipase domain containing 6)|
|Background||This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||patatin-like phospholipase domain containing 6 Antibody , NTEMND Antibody , sws Antibody , SPG39 Antibody , PNPLA6 Antibody , iPLA2delta Antibody|
|Cellular Localization||Endoplasmic reticulum membrane; Single-pass type I membrane protein; Cytoplasmic side |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human NTE. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chicken (94%), Bovine (98%)|