Full Name | numb homolog (Drosophila) |
Background | The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Synonyms | numb homolog (Drosophila) Antibody , C14orf41 Antibody , S171 Antibody , c14_5527 Antibody |
Specificity | At least four isoforms of NUMB are known to exist; this antibody will detect all of them. |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | NUMB antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human NUMB.The immunogen is located within the last 50 amino acids of NUMB. |
Antigen Species | Human |
Species Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |