|Full Name||numb homolog (Drosophila)|
|Product Description||Rabbit polyclonal antibody to NUMB (NUMB homolog (Drosophila))|
|Background||The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||S171 antibody, NUMB antibody, protein numb homolog antibody, h-Numb antibody, numb homolog (Drosophila) antibody|
|Cellular Localization||Membrane; Peripheral membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human NUMB. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Chicken, Bovine|
|Predict Reactivity Note||Rat (94%), Zebrafish (88%), Chicken (92%), Bovine (93%)|