|Full Name||nucleoporin 50kDa|
|Product Description||Rabbit Polyclonal antibody to NUP50 (nucleoporin 50kDa)|
|Background||The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||MGC39961 antibody, NPAP60 antibody, NPAP60L antibody, NUP50 antibody, nucleoporin Nup50 antibody, nuclear pore-associated protein 60L antibody, nuclear pore complex protein Nup50 antibody, 50 kDa nucleoporin antibody, nucleoporin 50kDa antibody|
|Cellular Localization||Nucleus , nuclear pore complex , Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side (By similarity) |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NUP50. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|