Full Name | nuclear RNA export factor 3 |
Background | This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq] |
Synonyms | NXF3 antibody, TAPL-3 antibody, TAP-like protein 3 antibody, nuclear RNA export factor 3 antibody |
Cellular Localization | Nucleus , Cytoplasm |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein encompassing a sequence within the center region of human NXF3. The exact sequence is proprietary. |
Antigen Species | Human |
Species Reactivity | Human |
Predicted Cross Reactivity species Predicted cross-reactivity: Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive. Please note that we are only able to guarantee products to work in applications and species in which they have been tested. | Chimpanzee |
Predict Reactivity Note | Chimpanzee (98%) |
Conjugation | Unconjugated |