|Full Name||NCK adaptor protein 2|
|Product Description||Rabbit Polyclonal antibody to Nck beta (NCK adaptor protein 2)|
|Background||This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Synonyms||GRB4 antibody, NCKbeta antibody, NCK2 antibody, SH2/SH3 adaptor protein NCK-beta antibody, "noncatalytic region of tyrosine kinase, beta antibody", cytoplasmic protein NCK2 antibody, NCK adaptor protein 2 antibody|
|Cellular Localization||Cytoplasm , Endoplasmic reticulum |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Nck beta. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Pig, Chicken, Bovine|
|Predict Reactivity Note||Mouse (95%), Rat (95%), Xenopus laevis (83%), Pig (90%), Chicken (92%), Bovine (90%)|