|Full Name||poliovirus receptor-related 2 (herpesvirus entry mediator B)|
|Product Description||Rabbit polyclonal antibody to PVRL2(CD112) (poliovirus receptor-related 2 (herpesvirus entry mediator B))|
|Background||This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Synonyms||CD112 antibody, HVEB antibody, PRR2 antibody, PVRR2 antibody, PVRL2 antibody, nectin-2 antibody, herpesvirus entry protein B antibody, poliovirus receptor-related protein 2 antibody, poliovirus receptor-like 2 antibody, poliovirus receptor-related 2 (herpesvirus entry mediator B) antibody|
|Cellular Localization||Cell membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Nectin 2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (80%), Rat (80%)|