|Full Name||serpin peptidase inhibitor, clade I (neuroserpin), member 1|
|Product Description||Rabbit polyclonal antibody to Neuroserpin (serpin peptidase inhibitor, clade I (neuroserpin), member 1)|
|Background||This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]|
|Synonyms||DKFZp781N13156 antibody, PI12 antibody, neuroserpin antibody, SERPINI1 antibody, PI-12 antibody, peptidase inhibitor 12 antibody, serpin I1 antibody, "serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1 antibody", "serpin peptidase inhibitor, clade I (neuroserpin), member 1 antibody"|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Neuroserpin. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Rhesus Monkey (100%)|