|Full Name||nucleophosmin (nucleolar phosphoprotein B23, numatrin)|
|Product Description||Rabbit Polyclonal antibody to Nucleophosmin (nucleophosmin (nucleolar phosphoprotein B23, numatrin))|
|Background||NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF (MIM 600160). NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia (AML; MIM 601626) (Garzon et al., 2008 [PubMed 18308931]).[supplied by OMIM]|
|Synonyms||B23 antibody, MGC104254 antibody, NPM antibody, NPM1 antibody, nucleolar protein NO38 antibody, numatrin antibody, "nucleophosmin/nucleoplasmin family, member 1 antibody", nucleophosmin antibody, "nucleophosmin (nucleolar phosphoprotein B23, numatrin) antibody"|
|Cellular Localization||Nucleus , nucleolus |
|Immunogen||Full length human Nucleophosmin Recombinant protein.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Rabbit, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (92%), Rat (91%), Dog (97%), Rabbit (96%), Chimpanzee (99%), Bovine (92%)|