|Full Name||purine nucleoside phosphorylase|
|Product Description||Rabbit Polyclonal antibody to Nucleoside phosphorylase (purine nucleoside phosphorylase)|
|Background||This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq]|
|Synonyms||FLJ94043 antibody, FLJ97288 antibody, FLJ97312 antibody, MGC117396 antibody, MGC125915 antibody, MGC125916 antibody, NP antibody, PRO1837 antibody, PUNP antibody, PNP antibody, purine nucleoside phosphorylase antibody, inosine phosphorylase antibody, purine-nucleoside:orthophosphate ribosyltransferase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Nucleoside phosphorylase. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (85%), Rhesus Monkey (95%), Bovine (88%)|