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1 .GTX45061 OAZ2 antibody, Internal

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OAZ2 antibody, Internal


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsWB
  • Species reactivityHuman
Cat No: GTX45061
Package Price Qty
50 μgUSD 339.00
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  • Anti-OAZ2 antibody, Internal used in Western Blot (WB). GTX45061
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  • Datasheet
  • Application Information: OAZ2 antibody, Internal

Catalog Number GTX45061
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Product Name OAZ2 antibody, Internal
See all OAZ2 products
ApplicationsWB
Application Note
Suggested dilutionReference
Western Blot (WB)0.2-2.5 ug/ml*  
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Target Size21 KDa (note)
Positive Controlshuman fetal liver
Form SuppliedLiquid
Concentration0.5-1 mg/ml
PurificationAffinity Purified

  • Specifications: OAZ2 antibody, Internal

Full Nameornithine decarboxylase antizyme 2
BackgroundThe protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamines. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 2, the second member of the antizyme family. Like antizyme 1, antizyme 2 has broad tissue distribution, inhibits ODC activity and polyamine uptake, and stimulates ODC degradation in vivo; however, it fails to promote ODC degradation in vitro. Antizyme 2 is expressed at lower levels than antizyme 1, but is evolutionary more conserved, suggesting it likely has an important biological role. Studies also show different subcellular localization of antizymes 1 and 2, indicating specific function for each antizyme in discrete compartments of the cell. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2014]
SynonymsOAZ2 Antibody
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenA synthetic peptide corresponding to an Internal region of Human OAZ2
Antigen SpeciesHuman
Species ReactivityHuman
Predict Reactivity NoteCow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
ConjugationUnconjugated

  • Storage Conditions: OAZ2 antibody, Internal

Storage Buffer1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Storage InstructionKeep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
OAZ2 antibody, Internal validated data
  • Anti-OAZ2 antibody, Internal used in Western Blot (WB). GTX45061
    • GTX45061 WB Image
      WB analysis of human fetal liver tissue using GTX45061 OAZ2 antibody at 0.2-1μg/ml.
      Top
  • Anti-OAZ2 antibody, Internal used in Western Blot (WB). GTX45061
    • GTX45061 WB Image
      WB analysis of human fetal liver tissue using GTX45061 OAZ2 antibody at 0.2-1μg/ml.
      Top
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All products are for research use only—Not for use in diagnostic procedures.