|Full Name||oral-facial-digital syndrome 1|
|Product Description||Rabbit Polyclonal antibody to OFD1 (oral-facial-digital syndrome 1)|
|Background||This gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified; a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome. Alternatively spliced transcripts have been described for this gene but the biological validity of these transcripts has not been determined. [provided by RefSeq]|
|Synonyms||71-7A antibody, CXorf5 antibody, JBTS10 antibody, MGC117039 antibody, MGC117040 antibody, SGBS2 antibody, OFD1 antibody, oral-facial-digital syndrome 1 protein antibody, protein 71-7A antibody, oral-facial-digital syndrome 1 antibody|
|Cellular Localization||Cytoplasm , Centrosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human OFD1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (80%)|