|Full Name||tumor necrosis factor receptor superfamily, member 11b|
|Product Description||Rabbit Polyclonal antibody to OPG (tumor necrosis factor receptor superfamily, member 11b)|
|Background||The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq]|
|Synonyms||MGC29565 antibody, OCIF antibody, OPG antibody, TR1 antibody, TNFRSF11B antibody, osteoprotegerin antibody, tumor necrosis factor receptor superfamily member 11B antibody, osteoclastogenesis inhibitory factor antibody, tumor necrosis factor receptor superfamily, member 11b antibody|
|Cellular Localization||Secreted |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human OPG. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (83%), Bovine (83%)|