|Full Name||origin recognition complex, subunit 2|
|Product Description||Rabbit polyclonal antibody to ORC2 (origin recognition complex, subunit 2-like (yeast))|
|Background||The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3L, -4L, and -5L. It also interacts with CDC45L and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. [provided by RefSeq]|
|Synonyms||ORC2L antibody, ORC2 antibody, origin recognition complex protein 2 homolog antibody, "origin recognition complex, subunit 2 homolog antibody", origin recognition complex subunit 2 antibody, "origin recognition complex, subunit 2 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ORC2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (84%), Rat (84%), Bovine (92%)|