|Full Name||osteopetrosis associated transmembrane protein 1|
|Product Description||Rabbit Polyclonal antibody to OSTM1 (osteopetrosis associated transmembrane protein 1)|
|Background||This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. [provided by RefSeq]|
|Synonyms||GIPN antibody, GL antibody, OPTB5 antibody, OSTM1 antibody, grey-lethal osteopetrosis antibody, GAIP-interacting protein N terminus antibody, osteopetrosis-associated transmembrane protein 1 antibody, osteopetrosis associated transmembrane protein 1 antibody|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human OSTM1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (81%), Rat (83%), Rabbit (92%), Rhesus Monkey (99%), Bovine (90%)|