|Full Name||ornithine carbamoyltransferase|
|Product Description||Rabbit Polyclonal antibody to OTC (ornithine carbamoyltransferase)|
|Background||This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. [provided by RefSeq]|
|Synonyms||MGC129967 antibody, MGC129968 antibody, MGC138856 antibody, OCTD antibody, OTC antibody, ornithine transcarbamylase antibody, OTCase antibody, "ornithine carbamoyltransferase, mitochondrial antibody", ornithine carbamoyltransferase antibody|
|Cellular Localization||Mitochondrion matrix |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human OTC. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chicken, Bovine|
|Predict Reactivity Note||Rat (93%), Pig (94%), Chicken (80%), Bovine (94%)|