|Full Name||OTU domain, ubiquitin aldehyde binding 1|
|Product Description||Rabbit Polyclonal antibody to OTUB1 (OTU domain, ubiquitin aldehyde binding 1)|
|Background||The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq]|
|Synonyms||FLJ20113 antibody, FLJ40710 antibody, MGC111158 antibody, MGC4584 antibody, OTB1 antibody, OTU1 antibody, OTUB1 antibody, otubain-1 antibody, ubiquitin thioesterase OTUB1 antibody, deubiquitinating enzyme OTUB1 antibody, ubiquitin-specific protease otubain 1 antibody, OTU domain-containing ubiquitin aldehyde-binding protein 1 antibody, ubiquitin-specific-processing protease OTUB1 antibody, OTU-domain Ubal-binding 1 antibody, "OTU domain, ubiquitin aldehyde binding 1 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human OTUB1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Bovine|
|Predict Reactivity Note||Dog (99%), Pig (100%), Bovine (100%)|