|Full Name||OTU domain containing 5|
|Product Description||Rabbit Polyclonal antibody to OTUD5 (OTU domain containing 5)|
|Background||This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]|
|Synonyms||DKFZp761A052 antibody, DUBA antibody, MGC104871 antibody, OTUD5 antibody, deubiquitinating enzyme A antibody, deubiquinating enzyme A antibody, OTU domain-containing protein 5 antibody, OTU domain containing 5 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human OTUD5. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (99%), Xenopus laevis (83%), Bovine (98%)|