|Full Name||cadherin 3, type 1, P-cadherin (placental)|
|Product Description||Rabbit Polyclonal antibody to P-cadherin (cadherin-3)|
|Background||This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq]|
|Synonyms||CDHP antibody, HJMD antibody, PCAD antibody, CDH3 antibody, "calcium-dependent adhesion protein, placental antibody", cadherin-3 antibody, "cadherin 3, type 1, P-cadherin (placental) antibody"|
|Cellular Localization||Cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human P-cadherin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (89%), Bovine (93%)|