|Full Name||purinergic receptor P2X, ligand-gated ion channel, 3|
|Product Description||Rabbit Polyclonal antibody to P2X3 (purinergic receptor P2X, ligand-gated ion channel, 3)|
|Background||The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq]|
|Synonyms||MGC129956 antibody, P2X3 antibody, P2RX3 antibody, P2X purinoceptor 3 antibody, "P2X receptor, subunit 3 antibody", purinoceptor P2X3 antibody, ATP receptor antibody, purinergic receptor P2X3 antibody, "purinergic receptor P2X, ligand-gated ion channel, 3 antibody"|
|Cellular Localization||Membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human P2X3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (94%), Rat (94%)|