|Full Name||prolyl 4-hydroxylase, alpha polypeptide I|
|Product Description||Rabbit Polyclonal antibody to P4HA1 (prolyl 4-hydroxylase, alpha polypeptide I)|
|Background||This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]|
|Synonyms||P4HA antibody, P4HA1 antibody, C-P4Halpha(I) antibody, collagen prolyl 4-hydroxylase alpha(I) antibody, "procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I antibody", "procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1 antibody", prolyl 4-hydroxylase subunit alpha-1 antibody, "prolyl 4-hydroxylase, alpha polypeptide I antibody"|
|Cellular Localization||Endoplasmic reticulum lumen |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human P4HA1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Chicken, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (95%), Pig (99%), Chicken (96%), Bovine (99%)|