|Full Name||poly(A) binding protein, cytoplasmic 1|
|Product Description||Rabbit Polyclonal antibody to PABP (polyadenylate-binding protein 1)|
|Background||The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4; MIM 603407), and PABP3 (PABPC3; MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.[supplied by OMIM]|
|Synonyms||PAB1 antibody, PABP antibody, PABP1 antibody, PABPC2 antibody, PABPL1 antibody, PABPC1 antibody, polyadenylate-binding protein 1 antibody, "poly(A) binding protein, cytoplasmic 2 antibody", "poly(A) binding protein, cytoplasmic 1 antibody"|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PABP. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Xenopus laevis (91%), Chicken (95%), Rhesus Monkey (100%), Bovine (100%)|