|Full Name||phosphofurin acidic cluster sorting protein 2|
|Product Description||Rabbit polyclonal antibody to PACS2 (phosphofurin acidic cluster sorting protein 2)|
|Background||Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.|
|Synonyms||FLJ25488 antibody, KIAA0602 antibody, PACS1L antibody, PACS2 antibody, phosphofurin acidic cluster sorting protein 2 antibody, PACS1-like protein antibody|
|Cellular Localization||Endoplasmic reticulum lumen , Mitochondrion |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human PACS2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Zebrafish|
|Predict Reactivity Note||Human (100%), Mouse (92%), Zebrafish (81%)|