Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||60 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)|
|Product Description||Rabbit polyclonal antibody to PAF1 (PAF1, RNA polymerase II associated factor, homolog (S. cerevisiae))|
|Background||PAF1, parafibromin (CDC73; MIM 607393), LEO1 (MIM 610507), and CTR9 (MIM 609366) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]). The PAF complex also has a role in histone monoubiquitination (Zhu et al., 2005 [PubMed 16307923]).[supplied by OMIM]|
|Synonyms||F23149_1 antibody, FLJ11123 antibody, PD2 antibody, PAF1 antibody, pancreatic differentiation protein 2 antibody, hPAF1 antibody, RNA polymerase II-associated factor 1 homolog antibody, "Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) antibody"|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PAF1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (96%), Chimpanzee (100%), Bovine (85%)|