|Full Name||p21 protein (Cdc42/Rac)-activated kinase 1|
|Product Description||Rabbit Polyclonal antibody to PAK1 (p21 protein (Cdc42/Rac)-activated kinase 1)|
|Background||PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternativelt spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||MGC130000 antibody, MGC130001 antibody, PAKalpha antibody, PAK1 antibody, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) antibody, alpha-PAK antibody, p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) antibody, p65-PAK antibody, serine/threonine-protein kinase PAK 1 antibody, STE20 homolog, yeast antibody, p21 protein (Cdc42/Rac)-activated kinase 1 antibody|
|Cellular Localization||Cytoplasm , Cell junction , focal adhesion |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PAK1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Zebrafish (90%), Xenopus laevis (85%), Chicken (96%), Bovine (99%)|