|Full Name||PAK1 interacting protein 1|
|Product Description||Rabbit polyclonal antibody to PAK1 interacting protein 1 (PAK1 interacting protein 1)|
|Background||Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.|
|Synonyms||FLJ20624 antibody, MAK11 antibody, PIP1 antibody, RP11-421M1.5 antibody, WDR84 antibody, bA421M1.5 antibody, hPIP1 antibody, PAK1IP1 antibody, PAK/PLC-interacting protein 1 antibody, p21-activated protein kinase-interacting protein 1 antibody, PAK1-interacting protein 1 antibody, WD repeat-containing protein 84 antibody, PAK1 interacting protein 1 antibody|
|Cellular Localization||Nucleus , nucleolus |
|Target||PAK1 interacting protein 1 |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PAK1 interacting protein 1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (81%), Rat (89%), Chicken (80%), Rhesus Monkey (100%), Bovine (87%)|