|Full Name||p21 protein (Cdc42/Rac)-activated kinase 6|
|Product Description||Rabbit Polyclonal antibody to PAK6 (serine/threonine-protein kinase PAK 6)|
|Background||This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||PAK5 antibody, PAK6 antibody, PAK-5 antibody, PAK-6 antibody, p21(CDKN1A)-activated kinase 6 antibody, serine/threonine-protein kinase PAK 6 antibody, p21-activated protein kinase 6 antibody, p21-activated kinase 6 antibody, p21 protein (Cdc42/Rac)-activated kinase 6 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PAK6. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (98%), Rhesus Monkey (99%), Bovine (98%)|