|Full Name||paired box 3|
|Product Description||Rabbit Polyclonal antibody to PAX3 (paired box 3)|
|Background||This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq]|
|Synonyms||CDHS antibody, HUP2 antibody, MGC120381 antibody, MGC120382 antibody, MGC120383 antibody, MGC120384 antibody, MGC134778 antibody, WS1 antibody, WS3 antibody, PAX3 antibody, paired box protein Pax-3 antibody, paired box homeotic gene 3 antibody, paired domain gene HuP2 antibody, paired domain gene 3 antibody, paired box 3 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human PAX3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Mouse (95%), Rat (95%), Xenopus laevis (90%), Chicken (97%), Bovine (98%)|