| Full Name | protocadherin alpha 10 |
| Product Description | Rabbit Polyclonal antibody to PCDHA10 |
| Background | This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants |
| Synonyms | PCDHA10 Antibody , PCDH ALPHA10 Antibody , CRNR8 Antibody , CNRS8 Antibody , CNR8 Antibody , CNRN8 Antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target | PCDHA10 |
| Isotype | IgG |
| Immunogen | A synthetic peptide corresponding to a N-terminal region of Human PCDHA10 |
| Antigen Species | Human |
| Species Reactivity | Human |
| Predict Reactivity Note | Cow: 79%; Dog: 79%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100% |
| Conjugation | Unconjugated |