|Full Name||proprotein convertase subtilisin/kexin type 9|
|Product Description||Rabbit polyclonal antibody to PCSK9 (proprotein convertase subtilisin/kexin type 9)|
|Background||This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq]|
|Synonyms||FH3 antibody, HCHOLA3 antibody, LDLCQ1 antibody, NARC-1 antibody, NARC1 antibody, PC9 antibody, PCSK9 antibody, subtilisin/kexin-like protease PC9 antibody, proprotein convertase subtilisin/kexin type 9 antibody, neural apoptosis regulated convertase 1 antibody, convertase subtilisin/kexin type 9 preproprotein antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NARC-1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Human (100%), Chimpanzee (100%)|