|Full Name||proprotein convertase subtilisin/kexin type 9|
|Product Description||Rabbit Polyclonal antibody to PCSK9 (proprotein convertase subtilisin/kexin type 9)|
|Background||This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq]|
|Synonyms||NARC1 Antibody , proprotein convertase subtilisin/kexin type 9 Antibody , NARC-1 Antibody , PC9 Antibody , HCHOLA3 Antibody , FH3 Antibody , LDLCQ1 Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PCSK9. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Mouse (82%), Rat (83%), Rhesus Monkey (96%), Chimpanzee (100%)|