|Full Name||programmed cell death 10|
|Product Description||Rabbit Polyclonal antibody to PDCD10|
|Background||This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]|
|Synonyms||TFAR15 Antibody, programmed cell death 10 Antibody, CCM3 Antibody|
|Immunogen||KLH conjugated synthetic peptide derived from humna PDCD10|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rabbit, Horse, Pig, Chicken|