|Full Name||phosphodiesterase 1A, calmodulin-dependent|
|Product Description||Rabbit Polyclonal antibody to PDE1A (calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A)|
|Background||Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM]|
|Synonyms||HCAM1 antibody, HSPDE1A antibody, MGC26303 antibody, PDE1A antibody, calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase antibody, "3',5' cyclic nucleotide phosphodiesterase antibody", "calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A antibody", phosphodiesterase-1A antibody, hCam-1 antibody, calmodulin-dependent phosphodiesterase antibody, cam-PDE 1A antibody, 61 kDa Cam-PDE antibody, "phosphodiesterase 1A, calmodulin-dependent antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PDE1A. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (93%), Dog (89%), Rhesus Monkey (97%), Chimpanzee (100%), Bovine (88%)|