|Full Name||phosphodiesterase 3A, cGMP-inhibited|
|Product Description||Rabbit Polyclonal antibody to PDE3A (phosphodiesterase 3A, cGMP-inhibited)|
|Background||Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least 5 major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).[supplied by OMIM]|
|Synonyms||CGI-PDE antibody, PDE3A antibody, cyclic GMP-inhibited phosphodiesterase A antibody, "cGMP-inhibited 3',5'-cyclic phosphodiesterase A antibody", "cAMP phosphodiesterase, myocardial cGMP-inhibited antibody", "phosphodiesterase 3A, cGMP-inhibited antibody"|
|Cellular Localization||Membrane; Peripheral membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PDE3A. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Pig (88%)|