|Full Name||platelet-derived growth factor receptor, alpha polypeptide|
|Product Description||Rabbit polyclonal antibody to PDGF Receptor alpha(CD140a) (platelet-derived growth factor receptor, alpha polypeptide)|
|Background||This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq]|
|Synonyms||CD140A antibody, MGC74795 antibody, PDGFR2 antibody, RHEPDGFRA antibody, PDGFRA antibody, CD140 antigen-like family member A antibody, CD140a antigen antibody, PDGF-R-alpha antibody, rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein antibody, platelet-derived growth factor receptor 2 antibody, platelet-derived growth factor receptor alpha antibody, platelet-derived growth factor alpha receptor antibody, alpha platelet-derived growth factor receptor antibody, PDGFRA/BCR fusion antibody, PDGFR-alpha antibody, alpha-type platelet-derived growth factor receptor antibody, "platelet-derived growth factor receptor, alpha polypeptide antibody"|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PDGF Receptor alpha. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chicken (86%), Bovine (96%)|