|Full Name||pyruvate dehydrogenase kinase, isozyme 4|
|Product Description||Rabbit polyclonal antibody to PDK4 (pyruvate dehydrogenase kinase, isozyme 4)|
|Background||This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq]|
|Synonyms||FLJ40832 antibody, PDK4 antibody, "pyruvate dehydrogenase kinase, isoenzyme 4 antibody", "pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial antibody", "pyruvate dehydrogenase kinase, isozyme 4 antibody", "[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial antibody"|
|Cellular Localization||Mitochondrion matrix|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PDK4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Pig, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (93%), Rat (93%), Pig (91%), Chicken (80%), Chimpanzee (99%), Bovine (90%)|