| Full Name | PDZ and LIM domain 3 |
| Product Description | Rabbit Polyclonal antibody to PDLIM3 (PDZ and LIM domain 3) |
| Background | The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
| Synonyms | ALP antibody, DKFZp686L0362 antibody, FLJ26096 antibody, PDLIM3 antibody, actinin-associated LIM protein antibody, enigma homolog antibody, alpha-actinin-2-associated LIM protein antibody, PDZ and LIM domain protein 3 antibody, PDZ and LIM domain 3 antibody |
| Cellular Localization | Cytoplasm , myofibril , sarcomere , Z-disk |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PDLIM3. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Pig, Rhesus Monkey, Bovine |
| Predict Reactivity Note | Pig (80%), Rhesus Monkey (100%), Bovine (93%) |
| Conjugation | Unconjugated |