|Full Name||PDZ domain containing 2|
|Product Description||Rabbit polyclonal antibody to PDZK3 (PDZ domain containing 2)|
|Background||Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq]|
|Synonyms||AIPC antibody, KIAA0300 antibody, PAPIN antibody, PDZK3 antibody, PIN1 antibody, PDZD2 antibody, PDZ domain containing 3 antibody, PDZ domain-containing protein 3 antibody, activated in prostate cancer protein antibody, PDZ domain-containing protein 2 antibody, PDZ domain containing 2 antibody|
|Cellular Localization||Nucleus (By similarity) , Cytoplasm , Endoplasmic reticulum , Processed PDZ domain-containing protein 2: Secreted |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PDZK3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (92%), Rat (92%)|