|Applications||ICC/IF, IP, WB|
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||136 kDa (note)
|Positive Controls||293T , HeLa , HepG2 , Drosophila , Rat2 , mouse brain , rat brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||period circadian clock 1|
|Product Description||Rabbit Polyclonal antibody to PER1 (period circadian clock 1)|
|Background||This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. Alternative splicing has been observed in this gene; however, these variants have not been fully described. [provided by RefSeq]|
|Synonyms||RIGUI Antibody, PER Antibody, period circadian clock 1 Antibody, hPER Antibody|
|Cellular Localization||Nucleus (By similarity) , Cytoplasm (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PER1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Drosophila, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (88%)|